Brand Name Nexium. Generic Name Esomeprazole. Nexium (Esomeprazole) is a Proton Pump Inhibitor (PPI) used to treat heartburn, or gastroesophageal reflux. It may be used in combination with two antibiotics to treat helicobacter pylori (h. Pylori) infection and duodenal ulcers. It may also be used to treat other conditions as determined by your doctor.
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